**Core Concept**
Chronic Cor pulmonale is a condition characterized by right ventricular failure due to pulmonary hypertension, often resulting from chronic lung disease. Radiological features of this condition can help in diagnosing and assessing its severity.

**Why the Correct Answer is Right**
Prominent lower lobe vessels are not typically seen in Chronic Cor pulmonale. In this condition, the upper lobe vessels are usually more prominent due to the increased pulmonary artery pressure, which causes vascular redistribution. This is in contrast to the normal distribution of pulmonary vessels, where both upper and lower lobe vessels are equally prominent. The correct radiological features of Chronic Cor pulmonale include increased pulmonary artery diameter, right ventricular enlargement, Kerley B lines, and pleural effusion.

**Why Each Wrong Option is Incorrect**
**Option A:** Kerley B lines are indeed a feature of Chronic Cor pulmonale, representing interstitial edema in the lung periphery.
**Option C:** Pleural effusion is also a common finding in Chronic Cor pulmonale, reflecting right-sided heart failure and fluid overload.
**Option D:** Cardiomegaly, specifically right ventricular enlargement, is a hallmark of Chronic Cor pulmonale, indicating right ventricular hypertrophy.

**Clinical Pearl / High-Yield Fact**
In Chronic Cor pulmonale, the upper lobe vessels are typically more prominent than the lower lobe vessels due to vascular redistribution. Remember the "upper lobe prominence" sign to distinguish this condition from other pulmonary vascular abnormalities.

✓ Correct Answer: B. Prominent lower lobe vessels