Radioisotope of choice for Triple phase Bone scan?
**Core Concept**
A triple phase bone scan is a diagnostic imaging technique used to assess bone metabolism and identify areas of abnormal bone activity. It involves the use of a radioactive tracer, specifically a radioisotope, to visualize bone tissue and detect various bone disorders.
**Why the Correct Answer is Right**
The radioisotope of choice for a triple phase bone scan is Technetium-99m (Tc-99m) labeled diphosphonate (Tc-99m MDP). This is because Tc-99m MDP has a suitable half-life, allowing for optimal imaging, and it selectively binds to hydroxyapatite in bone tissue, enabling the visualization of bone metabolism. This property enables the detection of areas of increased or decreased bone turnover.
**Why Each Wrong Option is Incorrect**
**Option A:** Technetium-99m has a suitable half-life, but it's not the correct form for bone scanning.
**Option B:** Gallium-67 is used for detecting inflammatory processes, not bone metabolism.
**Option C:** Indium-111 is used for imaging infections and tumors, not bone turnover.
**Clinical Pearl / High-Yield Fact**
A triple phase bone scan can help identify various bone disorders, including osteoporosis, bone tumors, and fractures, by assessing bone metabolism and detecting abnormal bone activity.
**Correct Answer: D. Technetium-99m labeled diphosphonate (Tc-99m MDP).**