Radiation exposure during infancy has been linked to which one of the following carcinoma –
**Core Concept**
Radiation exposure during infancy has been associated with an increased risk of developing certain types of cancer later in life. This is due to the high sensitivity of rapidly dividing cells, particularly in the developing fetus and young child.
**Why the Correct Answer is Right**
The correct answer is linked to the concept of carcinogenesis, specifically the induction of cancer by ionizing radiation. Ionizing radiation can cause DNA damage, leading to mutations in genes that regulate cell growth and division, ultimately resulting in cancer. In infancy, the developing brain and nervous system are particularly vulnerable to radiation-induced damage. The thyroid gland, which is also sensitive to radiation, has a high concentration of iodine and is a common site for radiation-induced cancer.
**Why Each Wrong Option is Incorrect**
**Option A:** Not directly linked to radiation exposure during infancy.
**Option B:** Not a well-established link between radiation exposure and this type of cancer in infancy.
**Option C:** Not a common site for radiation-induced cancer in infancy.
**Clinical Pearl / High-Yield Fact**
Radiation-induced cancer, particularly thyroid cancer, is a well-documented consequence of childhood exposure to ionizing radiation, as seen in the atomic bomb survivors and children exposed to radiation from nuclear accidents.
**Correct Answer: C. Thyroid carcinoma.**