**Core Concept**
Quincke's disease, also known as angioneurtic edema, is a condition characterized by the sudden onset of non-pitting edema involving the skin and mucous membranes. This condition typically affects the face, lips, tongue, and upper airway. The exact pathophysiology involves an allergic reaction to certain medications or foods, leading to the release of histamine and other vasoactive substances.

**Why the Correct Answer is Right**
Angioneurtic edema is caused by increased vascular permeability due to the release of histamine from mast cells. This leads to the movement of fluid from the blood vessels into the interstitial space, resulting in edema. The condition is often associated with an allergic reaction to medications such as aspirin, ibuprofen, or penicillin. The edema can be localized or generalized, and in severe cases, it can compromise the airway, leading to respiratory distress.

**Why Each Wrong Option is Incorrect**
**Option A:** Norwegian scabies is a highly contagious and severe form of scabies caused by a mutation in the scabies mite. It is not related to Quincke's disease.
**Option C:** Seborrheic oleosa is a type of seborrheic dermatitis characterized by an oily, yellowish crust on the skin. It is not associated with Quincke's disease.
**Option D:** Saddle nose is a condition where the nasal bridge is flattened or depressed, often due to trauma or congenital conditions. It is not related to Quincke's disease.

**Clinical Pearl / High-Yield Fact**
When suspecting angioneurtic edema, it is essential to identify and eliminate potential allergens, such as medications or foods, to prevent further episodes. Patients should be advised to carry an EpiPen or other emergency medication in case of severe reactions.

**✓ Correct Answer: B. Angioneuritic edema**