Metabolic disturbance seen with pyloric stenosis:March 2007, March 2013 (a, b, d, e)
**Core Concept**
The underlying principle being tested is the metabolic disturbance associated with **pyloric stenosis**, a condition characterized by the narrowing of the pyloric canal, leading to gastric outlet obstruction. This condition often presents with **vomiting**, which can cause various metabolic imbalances.
**Why the Correct Answer is Right**
Although the exact correct answer choice is not provided, typically, the metabolic disturbance seen with pyloric stenosis is **hypochloremic metabolic alkalosis**. This occurs due to the loss of hydrochloric acid (HCl) from the stomach through vomiting, leading to a decrease in chloride levels and an increase in bicarbonate levels, resulting in metabolic alkalosis.
**Why Each Wrong Option is Incorrect**
**Option A:** Would be incorrect if it suggested a different metabolic disturbance not associated with pyloric stenosis.
**Option B:** Similarly, would be incorrect if it did not align with the typical metabolic profile of pyloric stenosis.
**Option D:** Would be incorrect if it proposed a condition that does not result from the pathophysiology of pyloric stenosis.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that **hypochloremic metabolic alkalosis** is a classic finding in pyloric stenosis due to the loss of HCl through vomiting. Recognizing this association is crucial for diagnosing and managing the condition.
**Correct Answer:** Unfortunately, without the exact answer choices, the precise correct answer cannot be provided. However, typically, the correct answer would relate to **hypochloremic metabolic alkalosis**.