**Core Concept**
Pseudomonas aeruginosa is a gram-negative bacterium that often causes infections in immunocompromised individuals, particularly those with burns. Effective treatment of Pseudomonas infections requires antibiotics that target the bacterial cell wall or inhibit protein synthesis.

**Why the Correct Answer is Right**
Colistin is a polymyxin antibiotic that works by binding to the bacterial cell membrane, disrupting its structure, and ultimately leading to cell lysis. It is effective against Pseudomonas aeruginosa, including multidrug-resistant strains, and is often used in critically ill patients, such as those with severe burns. Colistin's mechanism of action involves the interaction with the bacterial lipopolysaccharide layer, which disrupts the cell membrane's integrity.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not provide a specific antibiotic effective against Pseudomonas.
**Option B:** This option is incorrect because it does not specify an antibiotic commonly used in burns patients or against Pseudomonas.
**Option D:** This option is incorrect because it does not mention an antibiotic effective against Pseudomonas or commonly used in burns patients.

**Clinical Pearl / High-Yield Fact**
Colistin is often used in combination with other antibiotics to treat Pseudomonas infections due to its potential nephrotoxicity and neurotoxicity. It is essential to monitor renal function and electrolyte levels when using colistin.

**Correct Answer: C. Colistin**