Pseudomembrane over tonsil and pharynx is caused by
## **Core Concept**
The question tests knowledge of infectious diseases, specifically those causing pseudomembranes in the throat. A pseudomembrane is a false membrane composed of coagulated exudate, bacteria, and cellular debris that forms on mucous membranes, often seen in infections.
## **Why the Correct Answer is Right**
The correct answer, **C. Corynebacterium diphtheriae**, is right because this bacterium is classically associated with diphtheria, an infection that often presents with a pseudomembrane covering the tonsils and pharynx. This pseudomembrane can cause airway obstruction and is a hallmark of the disease. **Corynebacterium diphtheriae** produces toxins that lead to local tissue damage and necrosis, resulting in the formation of this membrane.
## **Why Each Wrong Option is Incorrect**
- **Option A:** *Streptococcus pneumoniae* can cause various infections, including pharyngitis, but it is not typically associated with the formation of a pseudomembrane.
- **Option B:** *Arcanobacterium haemolyticum* can cause pharyngitis and skin infections but is not characteristically linked with pseudomembrane formation.
- **Option D:** *Fusobacterium necrophorum* is associated with Lemierre's syndrome, a severe infection that can cause abscesses and septic thrombophlebitis, but not typically pseudomembranes.
## **Clinical Pearl / High-Yield Fact**
A key clinical pearl is that diphtheria, caused by **Corynebacterium diphtheriae**, is preventable by vaccination. The presence of a pseudomembrane in the throat should prompt consideration of diphtheria, especially in areas with low vaccination rates or in individuals with uncertain vaccination status.
## **Correct Answer:** . Corynebacterium diphtheriae