Pseudocyst of pancreas develops after attack of acute pancreatitis
**Core Concept**
Pseudocyst of the pancreas is a complication of acute pancreatitis, characterized by the formation of a fluid collection in the pancreas or surrounding tissues. It occurs due to the enzymatic destruction of the pancreatic tissue and subsequent leakage of pancreatic juice into the surrounding area.
**Why the Correct Answer is Right**
The development of a pseudocyst is a result of the activation of pancreatic enzymes, leading to pancreatic necrosis and inflammation. The necrotic tissue is then liquefied, forming a collection of fluid that is rich in pancreatic enzymes, amylase, and lipase. This fluid collection is confined by a wall of fibrous tissue, which is formed as part of the healing process.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because pseudocyst formation is not typically associated with chronic pancreatitis, which is characterized by a different set of pathophysiological changes.
**Option B:** This option is incorrect because abscess formation is a different complication of acute pancreatitis, typically characterized by the presence of pus rather than a fluid collection.
**Option C:** This option is incorrect because walled-off necrosis is a complication of necrotizing pancreatitis, characterized by the presence of a collection of necrotic tissue surrounded by a wall of fibrous tissue, but it is not the same as a pseudocyst.
**Clinical Pearl / High-Yield Fact**
Pseudocysts of the pancreas can be managed conservatively with observation and supportive care, but larger pseudocysts or those that cause symptoms may require drainage or surgical intervention.
**Correct Answer: D. Pseudocyst formation is a known complication of acute pancreatitis.**