Psammoma bodies are seen in following except-
I remember they are commonly associated with papillary thyroid carcinoma. That's a key point. Also, they can be found in meningiomas. Oh, and in serous papillary tumors of the ovary. Wait, there's also a type of meningioma called psammomatous meningioma where they're abundant. So, the options might include these conditions.
The question is asking for the exception. Let me think of other tumors. For example, pheochromocytomas or adrenal tumors don't typically have psammoma bodies. Or maybe something like follicular thyroid carcinoma? Wait, follicular thyroid carcinoma usually doesn't have psammoma bodies because they are more characteristic of papillary type. So if one of the options is follicular thyroid carcinoma, that would be the correct answer here.
But wait, the options aren't listed here. The user provided the question without the options. Hmm. Maybe they are placeholders. Let me proceed with the structure. The core concept here is the identification of psammoma bodies in different pathological conditions. The correct answer would be the one that's not associated with them. The incorrect options would be those that are associated. So, for each incorrect option, I need to explain why they do have psammoma bodies. The correct answer would be the one that doesn't, like follicular thyroid carcinoma, or maybe some other tumor like medullary thyroid carcinoma? No, medullary is different. Maybe a different type of ovarian tumor? For example, mucinous tumors don't have psammoma bodies. So if the options include a mucinous tumor, that's the exception.
But since the user hasn't provided the actual options, I need to base my explanation on the general knowledge. The key is that psammoma bodies are in papillary thyroid, meningiomas, serous ovarian tumors, and psammomatous meningiomas. The exception would be a tumor not in that list. So, the correct answer is the one that's not in that group. Therefore, when explaining, I should highlight the association of psammoma bodies with papillary thyroid, meningiomas, etc., and point out the exception as the correct answer.
**Core Concept**
Psammoma bodies are concentrically laminated calcifications formed by metaplastic ossification. They are pathognomonic for **papillary thyroid carcinoma**, **meningiomas**, and **serous papillary ovarian carcinomas**, but absent in other tumor types.
**Why the Correct Answer is Right**
The correct answer is the tumor type not associated with psammoma bodies. For example, **follicular thyroid carcinoma** lacks psammoma bodies because it arises from follicular cells rather than papillary architecture. Psammoma bodies form via calcification of necrotic debris in fibrovascular stroma, a hallmark of papillary tumors.
**Why Each Wrong Option is Incorrect**
**Option A:** *Papillary thyroid carcinoma* contains psammoma bodies due to calcification of fibrovascular cores.