Pharmacology Which of the following antibiotic structurally resembles aminoacyl tRNA and also inhibits protein synthesis: A Puromycin. B Tetracycline. C Chloramphenicol. D Sulphonamides. 💡 Explanation Which of the following antibiotic structurally resembles aminoacyl tRNA and also inhibits protein synthesis: ✓ Correct Answer: A. Puromycin.