**Core Concept**
Pertussis, also known as whooping cough, is a highly contagious bacterial infection caused by *Bordetella pertussis*. It primarily affects infants and young children, leading to severe respiratory symptoms.
**Why the Correct Answer is Right**
The correct answer is related to the role of maternal antibodies in providing protection to infants against pertussis. Maternal antibodies are transferred to the fetus during pregnancy, providing temporary immunity to the newborn. However, this immunity wanes within the first few months, leaving infants vulnerable to infection. **Option a** is incorrect because maternal antibodies do not provide long-term protection against pertussis.
**Why Each Wrong Option is Incorrect**
* **Option b:** Fomites play a small role in the spread of pertussis. In reality, the primary mode of transmission is through respiratory droplets, such as those produced during coughing or sneezing. Fomites may contribute to secondary transmission but are not the primary means of spread.
* **Option c:** This statement is true. Pertussis is commonly seen in infants, who are at highest risk of developing severe symptoms and complications.
* **Option d:** This statement is also true. Males and females are equally affected by pertussis, with no significant gender predisposition.
**Clinical Pearl / High-Yield Fact**
It's essential to note that the Centers for Disease Control and Prevention (CDC) recommend that pregnant women receive a pertussis vaccination between 27 and 36 weeks of gestation to prevent transmission to their infants.
**Correct Answer: C.**
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