Proteasome inhibition is seen with
Correct Answer: Boezomib
Description: It is a proteasome inhibitor - an anticancer drugBoezomib was first approved for use in relapsing or refractory multiple myeloma and is now widely used in the first-line treatment of multiple myeloma. This agent is thought to exe its main cytotoxic effects through inhibition of the 26 S proteasome, which results in down-regulation of the nuclear factor kappa B (NF-kB) signaling pathway. Of note,inhibition of NF-kB has been shown to restore chemosensitivity.Ref: Sharma and Sharma 3rd ed/pg 871; Katzung; 13th edition; Page no: 971
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now