**Core Concept**
The Shine-Dalgarno sequence is a ribosomal binding site in prokaryotes that is essential for the initiation of protein synthesis. It is located on the mRNA, upstream of the start codon (AUG) and is complementary to a specific sequence on the 16S rRNA of the small subunit of the ribosome.
**Why the Correct Answer is Right**
The correct sequence next to the Shine-Dalgarno sequence in prokaryotes is the start codon, AUG, which is the first codon of the mRNA and serves as the initiation codon for protein synthesis. The ribosome binds to the Shine-Dalgarno sequence and then moves to the start codon, where translation begins. The start codon is recognized by the initiator tRNA, which brings the amino acid methionine to the ribosome.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because it does not specify the correct sequence that is recognized by the ribosome.
* **Option B:** This option is incorrect because it does not provide any relevant information about the initiation of protein synthesis in prokaryotes.
* **Option C:** This option is incorrect because it does not describe the correct sequence that is present next to the Shine-Dalgarno sequence.
**Clinical Pearl / High-Yield Fact**
The Shine-Dalgarno sequence is an essential component of the initiation of protein synthesis in prokaryotes, and its presence is critical for the accurate translation of mRNA into protein.
**Correct Answer: A. AUG**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.