FALSE with respect to Progestase is
**Core Concept**
Progestase is a type of progestin-only contraceptive, which functions by releasing a steady amount of progesterone to prevent ovulation and maintain a thin endometrium, thereby inhibiting implantation of a fertilized egg. This class of contraceptive is often used in women who are breastfeeding or have contraindications to estrogen-containing contraceptives.
**Why the Correct Answer is Right**
The correct answer is C because Progestase is actually an intravaginal ring, not a subdermal implant. It releases a steady amount of progesterone, which is absorbed through the vaginal mucosa, preventing ovulation and maintaining a thin endometrium. This is in contrast to subdermal implants, which release a steady amount of progesterone or levonorgestrel through the skin.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because while Progestase is indeed designed to release a steady amount of progesterone, the exact amount released per day is not specified as 65 mcg in the literature. The amount of progesterone released can vary depending on the specific formulation and the individual user.
**Option B:** This option is incorrect because the effective life of Progestase is not 1 year. The exact duration of efficacy can vary depending on the specific formulation and individual user factors, but it is generally recommended to be replaced every 1-2 months.
**Option D:** This option is incorrect because while Progestase can reduce menstrual blood loss, it is not a primary mechanism of action for this contraceptive. The reduction in menstrual blood loss is a secondary effect of the progestin-only therapy.
**Clinical Pearl / High-Yield Fact**
It is essential to remember that progestin-only contraceptives, such as Progestase, can have varying effects on menstrual bleeding patterns, including reduced menstrual blood loss, irregular bleeding, or breakthrough bleeding. This should be taken into account when counseling patients using these contraceptives.
**✓ Correct Answer: C. It is a subdermal implant**