**Core Concept**
The question tests the student's knowledge of pharmacological effects of certain drugs on urine color, which is a **clinical side effect**. This is related to the drug's **metabolism** and **excretion**.

**Why the Correct Answer is Right**
The correct answer is related to a drug that contains a chromogen, which is a group that can be converted to a pigment. This pigment is then excreted in the urine, giving it an orange color. The most common drug associated with this effect is **Rifampicin**, an antibiotic used to treat **tuberculosis**.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not contain a chromogen that would result in orange urine.
**Option B:** Similarly, this option does not have the necessary chemical structure to produce an orange pigment in urine.
**Option C:** This option is also incorrect as it lacks the specific pharmacological property of causing orange urine.
**Option D:** Although not specified, if this is not Rifampicin, it would not be correct due to the same reasoning as the other options.

**Clinical Pearl / High-Yield Fact**
A memorable point is that **Rifampicin** can cause **orange discoloration** of body secretions, including urine, sweat, and tears, due to its lipophilic nature and **hepatic metabolism**.

**Correct Answer:** D. Rifampicin.