**Core Concept:** Odds represent the likelihood of an event occurring, calculated as the probability (risk) divided by the probability (risk) of the opposite event. In this case, the event is Mr. Ram developing Acute Myocardial Infarction (AMI) in his lifetime, and the opposite event is not developing AMI in his lifetime.

**Why the Correct Answer is Right:** The correct answer is calculated as follows:

1. Probability of developing AMI in Ram's lifetime: 0.75 (given in the question)
2. Probability of not developing AMI in Ram's lifetime: 1 - 0.75 = 0.25
3. Calculate odds: (0.75) / (0.25) = 3

So, Mr. Ram's odds of developing AMI in his lifetime are 3:1 (three to one).

**Why Each Wrong Option is Incorrect:**

A. This answer does not address the calculation of odds based on the given probabilities.
B. Same as Option A.
C. Same as Option A.
D. Same as Option A.

**Clinical Pearl / High-Yield Fact:** Understanding odds ratios is crucial for interpreting medical studies, epidemiological data, and patient counseling. A higher odds ratio indicates a higher likelihood of an event occurring, while a lower odds ratio indicates a lower likelihood. For example, an odds ratio of 3 suggests that the risk of developing a disease is three times higher in a specific group compared to another group.

**Correct Answer:** Odds: 3 (Mr. Ram's odds of developing AMI in his lifetime)