Physiology The pressure between the layers of the pleura is negative due to the following reasons: A The thoracic wall and lungs recoil in opposite directions B Intra pulmonary pressure is negative C Trans pulmonary pressure is negative D The surfactant prevents the pulmonary collapse 💡 Explanation The pressure between the layers of the pleura is negative due to the following reasons: ✓ Correct Answer: A. The thoracic wall and lungs recoil in opposite directions