**Question:** A male who abstained from alcohol for 2 days presents with seizures. What is the appropriate treatment?

**Core Concept:** Alcohol withdrawal syndrome (AWS) is a potentially life-threatening condition that occurs due to abrupt cessation or significant reduction in alcohol consumption. Acute seizures can be a life-threatening complication of AWS, and prompt management is essential.

**Why the Correct Answer is Right:** The correct answer is "D" Phenobarbitone, an anti-convulsant drug, is the first-line treatment for alcohol withdrawal seizures. Phenobarbitone acts as a GABA agonist, thereby suppressing neuronal excitability and reducing seizure frequency and intensity.

**Why Each Wrong Option is Incorrect:**

A. "Lorazepam" is also an anti-convulsant drug, but it is a more potent benzodiazepine, which can accelerate the development of AWS, and is not the first-line treatment for alcohol withdrawal seizures.

B. "Percocet" is a combination of oxycodone and acetaminophen, which is not relevant to treating alcohol withdrawal seizures.

C. "Nicotinic acid" is a medication used to lower cholesterol levels and does not address the seizures in AWS.

**Clinical Pearl:**

- In cases of alcohol withdrawal seizures, the management should focus on prompt administration of appropriate anti-convulsant medications (such as Phenobarbitone) to prevent further seizures and reduce the risk of complications.

**Correct Answer:** D. Phenobarbitone