A male did not have alcohol for 2 days presented with seizures treatment given: AIIMS 13
**Question:** A male who abstained from alcohol for 2 days presents with seizures. What is the appropriate treatment?
**Core Concept:** Alcohol withdrawal syndrome (AWS) is a potentially life-threatening condition that occurs due to abrupt cessation or significant reduction in alcohol consumption. Acute seizures can be a life-threatening complication of AWS, and prompt management is essential.
**Why the Correct Answer is Right:** The correct answer is "D" Phenobarbitone, an anti-convulsant drug, is the first-line treatment for alcohol withdrawal seizures. Phenobarbitone acts as a GABA agonist, thereby suppressing neuronal excitability and reducing seizure frequency and intensity.
**Why Each Wrong Option is Incorrect:**
A. "Lorazepam" is also an anti-convulsant drug, but it is a more potent benzodiazepine, which can accelerate the development of AWS, and is not the first-line treatment for alcohol withdrawal seizures.
B. "Percocet" is a combination of oxycodone and acetaminophen, which is not relevant to treating alcohol withdrawal seizures.
C. "Nicotinic acid" is a medication used to lower cholesterol levels and does not address the seizures in AWS.
**Clinical Pearl:**
- In cases of alcohol withdrawal seizures, the management should focus on prompt administration of appropriate anti-convulsant medications (such as Phenobarbitone) to prevent further seizures and reduce the risk of complications.
**Correct Answer:** D. Phenobarbitone