**Core Concept**
Cirrhosis is a late stage of scarring (fibrosis) of the liver caused by many forms of liver diseases and conditions, such as hepatitis and chronic alcoholism. Special stains are used to identify specific histopathological features in liver biopsy samples.

**Why the Correct Answer is Right**
The correct answer is a special stain used to identify Mallory-Denk bodies, which are characteristic histopathological features of alcoholic hepatitis and cirrhosis. Mallory-Denk bodies are formed by the aggregation of intermediate filament proteins, particularly cytokeratins 8 and 18. They are often seen in the cytoplasm of hepatocytes in patients with alcoholic liver disease.

**Why Each Wrong Option is Incorrect**
* **Option A:** This is incorrect because PAS (Periodic Acid-Schiff) stain is used to identify glycogen, mucin, and other carbohydrate-containing substances in tissues, but it is not specifically used to identify Mallory-Denk bodies.
* **Option B:** This is incorrect because Prussian blue stain is used to identify iron deposits in tissues, which can be seen in patients with hemochromatosis or other iron overload conditions, but it is not used to identify Mallory-Denk bodies.
* **Option C:** This is incorrect because Sirius red stain is used to identify collagen fibers in tissues, which can be seen in patients with liver fibrosis, but it is not used to identify Mallory-Denk bodies.

**Clinical Pearl / High-Yield Fact**
Mallory-Denk bodies are a classic histopathological feature of alcoholic liver disease, and their presence can help to distinguish between alcoholic and non-alcoholic causes of liver cirrhosis.

**Correct Answer:** C. Orcein stain