**Core Concept**
The lifespan of red blood cells (RBCs) in premature neonates is an essential aspect of pediatric hematology. Premature infants have immature reticuloendothelial systems, which affect the clearance of senescent RBCs. This results in a shorter lifespan of RBCs in these patients.

**Why the Correct Answer is Right**
In premature neonates, the lifespan of RBCs is approximately 60-70 days, which is significantly shorter than the normal lifespan of 120 days in adults. This is due to the immaturity of the spleen and the reticuloendothelial system, which are responsible for the removal of aged and damaged RBCs from the circulation. As a result, premature infants require more frequent blood transfusions to maintain adequate hemoglobin levels.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because the normal lifespan of RBCs in adults is not applicable to premature neonates.
**Option B:** This option is incorrect because the lifespan of RBCs in premature neonates is not as long as that in term infants.
**Option C:** This option is incorrect because the lifespan of RBCs in premature neonates is not as short as that in conditions of severe hemolysis or hemolytic anemia.

**Clinical Pearl / High-Yield Fact**
Premature infants have a higher risk of anemia due to the shorter lifespan of RBCs, which can lead to complications such as respiratory distress, cardiac failure, and poor growth and development.

**Correct Answer:** C. 70 days