**Core Concept**
Biosafety level III (BSL-III) is a laboratory containment level designed to handle microorganisms that can cause severe disease but for which vaccines or treatments are available. This level requires specialized facilities and equipment to prevent accidental exposure.

**Why the Correct Answer is Right**
BSL-III is typically practiced for agents that pose a moderate risk of inhalational transmission, such as Bacillus anthracis, Brucella species, and Mycobacterium tuberculosis. The use of BSL-III involves the use of a biological safety cabinet, primary containment devices, and secondary containment devices to prevent exposure. The microorganisms handled in this level are usually those that can cause serious disease but are manageable with proper treatment.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it's a common agent that would be handled in BSL-III.
**Option C:** This option is incorrect because it's a common agent that would be handled in BSL-III.

**Clinical Pearl / High-Yield Fact**
One important consideration when handling microorganisms at BSL-III is the use of personal protective equipment, including a face shield, gloves, and a lab coat, to prevent exposure.

**Correct Answer:** D.