**Core Concept**
The Prausnitz-Kustner reaction is a classic immunological phenomenon demonstrating the transfer of antibodies from one individual to another, resulting in the passive transfer of hypersensitivity. This reaction is a key concept in understanding the role of antibodies in mediating allergic reactions and anaphylaxis.

**Why the Correct Answer is Right**
The Prausnitz-Kustner reaction involves the transfer of serum containing IgE antibodies from an allergic individual to a non-allergic individual. When the serum is injected into the non-allergic individual, they develop an allergic reaction to the antigen, even if they were not previously exposed to it. This reaction is mediated by the IgE antibodies, which bind to the antigen and trigger the release of histamine and other chemical mediators from mast cells, leading to symptoms such as itching, swelling, and anaphylaxis. The Prausnitz-Kustner reaction is a crucial demonstration of the role of antibodies in mediating allergic reactions.

**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because the Prausnitz-Kustner reaction specifically involves the transfer of IgE antibodies, not IgG or IgM antibodies, which are not responsible for mediating allergic reactions.
* **Option B:** This option is incorrect because the Prausnitz-Kustner reaction is a passive transfer reaction, not an active immunization reaction, where the recipient's immune system is actively responding to the antigen.
* **Option C:** This option is incorrect because the Prausnitz-Kustner reaction is specific to IgE-mediated hypersensitivity reactions, not a general reaction to any type of antigen.

**Clinical Pearl / High-Yield Fact**
The Prausnitz-Kustner reaction is a classic example of the importance of IgE antibodies in mediating allergic reactions, and it has significant implications for the diagnosis and treatment of allergic diseases, such as anaphylaxis and asthma.

**Correct Answer:** D.