Positively charged particle can be easily filtered than negatively charged particle because
**Core Concept**
The question is testing the concept of ionic charge and its effect on diffusion and filtration in biological systems. In the context of renal physiology, positively charged particles, or cations, are more easily filtered through the glomerular basement membrane than negatively charged particles, or anions.
**Why the Correct Answer is Right**
The reason for this phenomenon lies in the presence of negatively charged molecules, such as glycoproteins and proteoglycans, in the glomerular basement membrane. These negatively charged molecules, known as fixed anions, repel negatively charged particles, making it more difficult for them to pass through the glomerular filtration barrier. On the other hand, positively charged particles are attracted to the negatively charged fixed anions, facilitating their passage through the glomerulus. This concept is crucial in understanding the differential filtration of ions and molecules in the kidneys.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because it does not provide a valid reason for the easier filtration of positively charged particles.
* **Option B:** This option is incorrect because it is too vague and does not specifically address the concept of ionic charge and its effect on filtration.
* **Option C:** This option is incorrect because it is not relevant to the concept of ionic charge and its effect on filtration in the kidneys.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that the glomerular filtration barrier is a dynamic structure that allows for the selective filtration of ions and molecules based on their charge, size, and other properties. This concept is crucial in understanding various renal disorders, such as nephrotic syndrome, where the glomerular basement membrane is altered, leading to the loss of negatively charged molecules and impaired filtration of negatively charged particles.
**Correct Answer:** C.