**Core Concept**
Polyhydramnios, a condition characterized by an excessive amount of amniotic fluid, is often associated with fetal anomalies or maternal diabetes mellitus. The underlying pathophysiological mechanism involves impaired fetal swallowing and/or impaired maternal glucose metabolism.
**Why the Correct Answer is Right**
The correct answer is associated with impaired fetal swallowing, which is a common cause of polyhydramnios. This can occur due to fetal anomalies such as esophageal atresia or duodenal atresia, which impede the normal swallowing process. In addition, maternal diabetes mellitus can also contribute to polyhydramnios due to fetal macrosomia and impaired fetal swallowing.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because it is not a known cause of polyhydramnios. **Option B:** This option is incorrect because it is a known cause of polyhydramnios, similar to maternal diabetes mellitus. **Option C:** This option is incorrect because it is not a direct cause of polyhydramnios, although it can be associated with other conditions that may contribute to polyhydramnios.
**Clinical Pearl / High-Yield Fact**
A classic mnemonic to remember the causes of polyhydramnios is "DIAMOND": Diabetes, Intrauterine growth restriction, Anencephaly, Maternal connective tissue disease, Oesophageal atresia, Neural tube defects, and Duodenal atresia.
**Correct Answer: A.**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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