**Core Concept**
Copper sulfate is a highly toxic compound that can cause significant damage to the body upon ingestion or exposure. The toxic effects of copper sulfate are primarily due to the release of copper ions, which can bind to various cellular components and disrupt normal cellular function.

**Why the Correct Answer is Right**
Copper sulfate poisoning is known to cause acute hemolysis due to the oxidative damage caused by the copper ions. Copper can bind to hemoglobin, leading to the formation of methemoglobin, which is unable to release oxygen to tissues. This results in a decrease in oxygen delivery to tissues, leading to acute hemolysis. Additionally, copper can also cause damage to the red blood cell membrane, leading to their destruction. The acute hemolysis is a direct consequence of the toxic effects of copper sulfate on the red blood cells.

**Why Each Wrong Option is Incorrect**
**Option A:** High anion gap acidosis is not a characteristic feature of copper sulfate poisoning. While it can cause metabolic acidosis, it is more commonly associated with other toxicities such as salicylate or methanol poisoning.

**Option B:** Rhabdomyolysis is not typically associated with copper sulfate poisoning. Rhabdomyolysis is more commonly seen in cases of severe crush injuries, heat stroke, or certain drug toxicities.

**Option D:** Peripheral neuropathy is not a characteristic feature of copper sulfate poisoning. While copper can accumulate in the nervous system and cause damage, peripheral neuropathy is more commonly associated with other heavy metal toxicities such as lead or arsenic.

**Clinical Pearl / High-Yield Fact**
It is essential to note that the clinical presentation of copper sulfate poisoning can vary depending on the dose and duration of exposure. Early recognition and treatment are critical to prevent further damage and improve outcomes.

**✓ Correct Answer: C. Acute hemolysis**