- PCV 23 vaccine is recommended for, - Older people > 65 years age - 2-64 years age if they have, Chronic cardiovascular disease Chronic pulmonary disease Diabetes mellitus Alcoholic Chronic smokers Chronic liver disease / cirrhosis Asplenia like sickle cell disease or splenectomy Immunosuppressed like HIV Organ transplantation Renal disease / transplantation - For children < 2 years age, PCV- 23 is strictly contraindicated.