Plaques with silvery scales over back are a characteristic feature of lesion of?
**Core Concept**
Psoriasis is a chronic autoimmune skin condition characterized by the formation of erythematous plaques with silvery scales. This condition results from an abnormal immune response, leading to excessive proliferation of skin cells.
**Why the Correct Answer is Right**
The correct answer is a result of the pathophysiology of psoriasis, where an abnormal immune response triggers the release of pro-inflammatory cytokines, which in turn stimulate the proliferation of skin cells. This leads to the formation of thick, scaly plaques. The silvery scales are a result of the accumulation of dead skin cells.
**Why Each Wrong Option is Incorrect**
* **Option A:** While seborrheic dermatitis can cause erythematous plaques, it is typically associated with a greasy, yellowish scale rather than a silvery one.
* **Option B:** Eczema, or atopic dermatitis, can cause erythematous plaques, but they are typically accompanied by intense itching and a lack of silvery scales.
* **Option C:** Lichen planus can cause purplish, itchy plaques, but they are not typically associated with silvery scales.
**Clinical Pearl / High-Yield Fact**
Psoriasis is associated with an increased risk of cardiovascular disease, diabetes, and depression, making it essential to consider these comorbidities in patients with psoriasis.
**Correct Answer: D. Psoriasis**