Plane was are caused by which of the following HPV types.
**Core Concept**
Plane warts, also known as flat warts, are a type of skin lesion caused by human papillomavirus (HPV). They typically appear as flat, smooth, flesh-colored or light-brown patches on the skin. Plane warts are often mistaken for other types of skin lesions due to their flat appearance.
**Why the Correct Answer is Right**
Plane warts are primarily caused by HPV types 3 and 10, which are part of the HPV-3 and HPV-10 species. These viruses lead to the formation of flat warts by infecting the epidermal cells and causing abnormal cell growth. The exact mechanism involves the integration of viral DNA into the host genome, leading to the expression of viral oncogenes that disrupt normal cell cycle regulation.
**Why Each Wrong Option is Incorrect**
**Option A:** Other HPV types, such as HPV-2 and HPV-4, are associated with common warts, not plane warts.
**Option B:** HPV-16 and HPV-18 are primarily linked to cervical cancer and other anogenital cancers, not plane warts.
**Option C:** HPV-6 and HPV-11 are associated with genital warts and laryngeal papillomas, not plane warts.
**Clinical Pearl / High-Yield Fact**
Plane warts can be treated with topical salicylic acid, cryotherapy, or other local therapies. It's essential to accurately diagnose plane warts to avoid mistreatment of other skin lesions.
**Correct Answer:** C. HPV-10.