Pink disease or acrodynia is seen with –
**Core Concept**
Pink disease or acrodynia is a rare condition characterized by inflammation of the skin and peripheral nerves, typically seen in children. It is associated with exposure to mercury, particularly in the form of calomel (mercurous chloride), which was used in teething powders and other products.
**Why the Correct Answer is Right**
The condition is thought to occur due to the toxic effects of mercury on the nervous system, particularly the peripheral nerves. Mercury is a potent neurotoxin that can cause demyelination and axonal damage, leading to symptoms such as pain, numbness, and tingling in the hands and feet. The condition is often seen in children who are exposed to mercury in teething powders or other products.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as pink disease is not associated with lead exposure. Lead is a different heavy metal that can cause a range of health problems, including neurological damage and developmental delays.
**Option B:** This option is incorrect as pink disease is not caused by arsenic exposure. Arsenic is a toxic substance that can cause a range of health problems, including skin lesions and cancer.
**Option C:** This option is incorrect as pink disease is not caused by fluoride exposure. Fluoride is a substance that is often used to prevent tooth decay, but it is not associated with the development of pink disease.
**Clinical Pearl / High-Yield Fact**
Pink disease is a classic example of a condition that was caused by exposure to a toxic substance, and it highlights the importance of careful regulation of products that contain heavy metals.
**Correct Answer:** C. Mercury