Pathology Pick the true statement about major criteria of Jones in acute rheumatic fever. A Carditis is the earliest clinical manifestation seen in acute rheumatic fever B Sydenham chorea is a late manifestation C Involvement of small joints is a characteristic feature D Subcutaneous nodule are seen on flexor aspects of the limbs 💡 Explanation Pick the true statement about major criteria of Jones in acute rheumatic fever. ✓ Correct Answer: B. Sydenham chorea is a late manifestation