Phospholipase C acts as second messenger for which of the following hormones?
Correct Answer: GnRH
Description: GnRH receptors are a pa of G protein coupled receptor superfamily and it functions primarily through the phospholipase C induced diacylglycerol and inositol triphosphate second messenger system. Second messengers used by hormones: CRH, ACTH, LH, FSH, TSH, PTH, calcitonin, glucagon, ADH (V2 receptor), hCG: increase cAMP. Prolactin: decrease cAMP. GHRH, GnRH, TRH, ADH (V1 receptor), oxytocin: DAG, IP3. Coisol, aldosterone, testosterone, estrogen, progesterone, calcitriol, thyroid hormones: Steroid mechanism. NO: cGMP. Insulin and IGF-1: Tyrosine kinase. Ref: Physiology By Robin R. Preston, page 439
Category:
Physiology
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