Pharyngoconjunctival fever type of acute follicular conjunctivitis is not caused by which of the following strain of Adenovirus?
**Core Concept**
Pharyngoconjunctival fever (PCF) is a type of acute follicular conjunctivitis caused by certain strains of Adenovirus. This condition is characterized by the triad of conjunctivitis, fever, and pharyngitis. The pathogenesis of PCF involves the replication of Adenovirus in the conjunctiva and the pharynx, leading to an inflammatory response.
**Why the Correct Answer is Right**
Pharyngoconjunctival fever is typically caused by Adenovirus serotypes 3, 4, and 7. These serotypes are known to replicate in the conjunctiva and pharynx, causing the characteristic symptoms of PCF. The correct answer is the Adenovirus serotype that is not typically associated with PCF.
**Why Each Wrong Option is Incorrect**
**Option A:** Adenovirus serotype 3 is a common cause of PCF, so this option is incorrect.
**Option B:** Adenovirus serotype 4 is also a known cause of PCF, making this option incorrect as well.
**Option C:** Adenovirus serotype 7 is another serotype that is associated with PCF, so this option is incorrect.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that Adenovirus serotypes 3, 4, and 7 are the most common causes of PCF, and these patients often present with a triad of conjunctivitis, fever, and pharyngitis.
**Correct Answer:** D.