**Core Concept**
Ectopic phaeochromocytomas are rare, extra-adrenal tumors that arise from chromaffin cells outside the adrenal glands. These cells are part of the sympathetic nervous system, which is responsible for the 'fight or flight' response.
**Why the Correct Answer is Right**
The most common site for ectopic phaeochromocytomas is the organ of Zuckerkandl, a small body of chromaffin tissue located near the bifurcation of the aorta. This location is significant because it's a site where chromaffin cells are most likely to be found outside the adrenal glands. The organ of Zuckerkandl is a common site for these tumors due to the presence of chromaffin cells, which can give rise to phaeochromocytoma.
**Why Each Wrong Option is Incorrect**
**Option A:** The paravertebral sympathetic ganglia are another site where chromaffin cells can be found, but they are not the most common location for ectopic phaeochromocytomas. These tumors are relatively rare in this location.
**Option B:** The thoracic and abdominal sympathetic chains are also sites where chromaffin cells can be found, but they are not the most common location for ectopic phaeochromocytomas.
**Option D:** While the adrenal glands are the most common site for phaeochromocytomas, ectopic tumors arising from chromaffin cells outside the adrenal glands are rare and typically occur in other locations.
**Clinical Pearl / High-Yield Fact**
Ectopic phaeochromocytomas can be challenging to diagnose due to their rarity and variable presentation. They can produce excess catecholamines, leading to symptoms such as hypertension, tachycardia, and sweating.
**Correct Answer: C. Organ of Zuckerkandl**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.