A 42 year old male after being influenced by online weight losing program decides to do an intense workout at gym. But he noticed that even after 45 minutes of workout he didn’t sweat. After that he went for steam bath and then also there was no perspiration. He noticed this from last few days and repoed to Medicine opd for the same . what could be the possible cause for this ?

**Core Concept**
The patient's inability to sweat, despite exposure to heat, suggests a disorder of the thermoregulatory system, specifically involving the eccrine glands, which are responsible for sweating.

**Why the Correct Answer is Right**
The patient's symptoms are consistent with Anhidrosis, a condition characterized by a reduced or absent ability to sweat. This could be due to various reasons, including neurological disorders, such as peripheral neuropathy or multiple system atrophy, which affect the autonomic nervous system responsible for controlling sweat glands. Another possibility is a primary anhidrotic disorder, such as congenital anhidrosis, which is a rare genetic condition affecting the eccrine glands. In some cases, anhidrosis can also be a side effect of certain medications, such as beta-blockers or anticholinergics.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is not relevant to the patient's symptoms, as it does not address the issue of anhidrosis.
**Option B:** While this option mentions a possible cause of anhidrosis, it is not the most likely explanation in this case, as there is no mention of a neurological disorder.
**Option C:** This option is incorrect because it does not address the issue of anhidrosis, and instead mentions a condition that is unrelated to the patient's symptoms.

**Clinical Pearl / High-Yield Fact**
It is essential to note that anhidrosis can be a sign of an underlying serious condition, such as multiple system atrophy or peripheral neuropathy, and therefore, a thorough investigation is necessary to determine the underlying cause.

**Correct Answer: D.**

✓ Correct Answer: B. Sudomotor failure