**Core Concept**
Peripheral neuropathy is a common side effect of certain antiretroviral drugs used in the treatment of HIV/AIDS. It is characterized by damage to the peripheral nerves, leading to pain, numbness, and weakness in the hands and feet.

**Why the Correct Answer is Right**
The correct answer is **Didanosine (ddI)**. Didanosine is a nucleoside reverse transcriptase inhibitor (NRTI) that can cause peripheral neuropathy as a side effect. This is due to its mechanism of action, which involves the inhibition of mitochondrial DNA polymerase gamma, leading to mitochondrial dysfunction and nerve damage. In contrast, other antiretroviral drugs such as Stavudine (d4T) and Zalcitabine (ddC) are also NRTIs that can cause peripheral neuropathy.

**Why Each Wrong Option is Incorrect**
**Option A:** Stavudine (d4T) - This NRTI is known to cause peripheral neuropathy, particularly at high doses.
**Option B:** Zalcitabine (ddC) - This NRTI is also associated with peripheral neuropathy, making it an incorrect choice.
**Option C:** Lamivudine (3TC) - This NRTI is generally well-tolerated and not associated with peripheral neuropathy.

**Clinical Pearl / High-Yield Fact**
It's essential to note that peripheral neuropathy can be a dose-limiting side effect of certain antiretroviral drugs, and patients should be closely monitored for symptoms such as numbness, tingling, and pain in the hands and feet.

**Correct Answer:** C. Lamivudine (3TC)