Perforins are produced by:
Correct Answer: Cytotoxic T cells
Description: Perforins are hole forming proteins synthesized by cytotoxic T-cells. They can perforate the plasma membrane of the target cells that are under attack by CD8+ lymphocytes. Granzymes are delivered into the target cells through these holes formed by perforins. In addition, the perforin pores allow water to enter the cells, thus causing osmotic lysis.
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now