Peliosis hepatis is caused by all except –
**Core Concept**
Peliosis hepatis is a rare condition characterized by the presence of blood-filled cavities or cysts within the liver, often associated with various underlying conditions. This condition can lead to liver dysfunction and potentially life-threatening complications.
**Why the Correct Answer is Right**
Peliosis hepatis is typically associated with the use of anabolic steroids, which can cause liver damage and lead to the formation of blood-filled cavities. The exact mechanism is not fully understood, but it is believed to involve the disruption of normal liver architecture and the formation of abnormal blood vessels. Other conditions associated with peliosis hepatis include certain infections, such as tuberculosis, and malignancies, such as hepatocellular carcinoma.
**Why Each Wrong Option is Incorrect**
**Option A:** Androgenic anabolic steroids are a well-known cause of peliosis hepatis, so this option is correct and should be excluded from the incorrect options.
**Option B:** Certain infections, including tuberculosis, have been linked to peliosis hepatis, making this option incorrect.
**Option C:** Malignancies, such as hepatocellular carcinoma, have been associated with peliosis hepatis, so this option is incorrect.
**Option D:** Oral contraceptives are not typically associated with peliosis hepatis, making this the correct answer.
**Clinical Pearl / High-Yield Fact**
Peliosis hepatis is a rare condition that can be associated with various underlying conditions, including the use of anabolic steroids, infections, and malignancies. It is essential to consider this condition in the differential diagnosis of patients with liver dysfunction or abnormalities on imaging studies.
**Correct Answer: D. Oral contraceptives are not typically associated with peliosis hepatis.