Patient with hemophilia A have bleeding disorder because of
Correct Answer: Lack of factor VIII a during activation of factor X in coagulation coscade
Description: Hemophilia A
X - linked disorder
90% cases - deficiency of factor 8
10% cases functional defect of factor 8
Factor VIII a complex is the most important activator of factor X required for conversion of prothrombin to thrombin.
Category:
Pathology
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