Patient complaints of muscle weakness. It was rivers on administration of neostigmine because
Correct Answer: Interferes with the action of Acetyl chlolinesterase
Description: (Ref: Katzung 11/e p105) Neostigmine acts by inhibiting the enzyme acetylcholinesterase. This enzyme is involved in degradation of ACh,consequently neostigmine inereases the synaptic level of ACh. Muscle weakness can be improved by stimulation of NM receptors at muscle end plate due to increased ACh.
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