Medical MCQ - Patient complaints of muscle weakness. It was rivers on administration of neostigmine because

Patient complaints of muscle weakness. It was rivers on administration of neostigmine because

It blocks action of acetylcholine

It interferes with the action of monoamine oxidase

It interferes with the action of carbonic anhydrase

Interferes with the action of Acetyl chlolinesterase

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Correct Answer:

Interferes with the action of Acetyl chlolinesterase

Description:

(Ref: Katzung 11/e p105) Neostigmine acts by inhibiting the enzyme acetylcholinesterase. This enzyme is involved in degradation of ACh,consequently neostigmine inereases the synaptic level of ACh. Muscle weakness can be improved by stimulation of NM receptors at muscle end plate due to increased ACh.

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