All of the following are pathologic features of brain in AIDS, EXCEPT:
**Core Concept**
In AIDS, the brain is affected by opportunistic infections and neoplasms, leading to various pathologic features. These changes are primarily due to the compromised immune system of the patient, which makes them susceptible to opportunistic pathogens.
**Why the Correct Answer is Right**
The pathologic features of the brain in AIDS include opportunistic infections such as Toxoplasma gondii, Cryptococcus neoformans, and Cytomegalovirus (CMV). These pathogens cause inflammation and tissue damage in the brain, leading to symptoms such as seizures, confusion, and headaches. Additionally, neoplasms like Primary CNS Lymphoma (PCNSL) can also occur in AIDS patients.
**Why Each Wrong Option is Incorrect**
**Option A:** is a likely pathologic feature of the brain in AIDS as Toxoplasma gondii is a common opportunistic infection in immunocompromised patients. However, the specific details of the feature are not provided, so we cannot rule it out as an incorrect option.
**Option B:** is incorrect as it is a common pathologic feature of the brain in AIDS. Cryptococcus neoformans is an opportunistic fungus that can cause meningitis and brain abscesses in immunocompromised patients.
**Option C:** is incorrect as it is a common pathologic feature of the brain in AIDS. Cytomegalovirus (CMV) is a common opportunistic virus that can cause encephalitis and retinitis in immunocompromised patients.
**Clinical Pearl / High-Yield Fact**
AIDS patients are prone to opportunistic infections and neoplasms due to their compromised immune system. These infections can cause a wide range of symptoms, including seizures, confusion, and headaches.
**Correct Answer:** D