Parvovirus infection which of the following is true
Correct Answer: Erythroid progenitors are affected
Description: Ref. Robbins Pathology. 9th edition. Page. 460
Parvovirus B19 directly infects eiythroid progenitors through the P antigen on erythroblast surface.
Individuals who lack P antigen are resistant to parvovirus infection.
Few giant proerythroblasts (GFE) with basophilic cytoplasm 'dogear1 like cytoplasmic projections, stippled chromatin and inclusion like nucleoli are characteristic and diagnostic of parvovirus BI9 infection
Parvovirus B19 infection usually remits spontaneously though few cases may require I/V Ig therapy
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