A 40-year-old woman presents with a painless mass anterior to her left ear. The mass had been slowly enlarging over the past year. The mass is firm and nontender. Computed tomography and magnetic resonance imaging reveal a well-circumscribed, homogeneous mass within the left parotid gland. Biopsy reveals anastomosing strands of stellate and fusiform epithelial cells embedded in a myxoid stroma. Which of the following is a characteristic of the lesion?
A 40-year-old woman presents with a painless mass anterior to her left ear. The mass had been slowly enlarging over the past year. The mass is firm and nontender. Computed tomography and magnetic resonance imaging reveal a well-circumscribed, homogeneous mass within the left parotid gland. Biopsy reveals anastomosing strands of stellate and fusiform epithelial cells embedded in a myxoid stroma. Which of the following is a characteristic of the lesion?
💡 Explanation
**Core Concept**
The underlying principle being tested is the identification of a specific type of salivary gland tumor, likely a **pleomorphic adenoma**, based on its histological characteristics. This tumor is the most common type of salivary gland tumor, often presenting as a slow-growing, painless mass. The diagnosis involves understanding the **histopathological features** of salivary gland tumors.
**Why the Correct Answer is Right**
The description of anastomosing strands of stellate and fusiform epithelial cells embedded in a myxoid stroma is characteristic of a **pleomorphic adenoma**. This type of tumor is known for its diverse cellular composition and architecture, which can include both epithelial and mesenchymal elements. The presence of a myxoid stroma, along with the specific types of epithelial cells mentioned, is highly suggestive of this diagnosis.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because it does not match the description provided.
**Option B:** Incorrect as it is not relevant to the histological features described.
**Option C:** Incorrect because the description does not align with the typical characteristics of this option.
**Option D:** Incorrect as the provided details do not correspond with the expected features of this choice.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that **pleomorphic adenomas** are benign tumors but have the potential for malignant transformation if left untreated. They are also known for their high recurrence rate if not completely excised.
**Correct Answer:** D. Benign behavior despite potential for malignant transformation and high recurrence rate if not completely excised.
✓ Correct Answer: D. Recurrence often takes place after surgical resection
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