## **Core Concept**
Para-aminobenzoic acid (PABA) is a naturally occurring compound found in certain foods and also produced by some bacteria. It acts as an intermediate in the synthesis of folic acid. In the context of breast milk and infection prevention, PABA has been associated with protection against a specific type of infection.
## **Why the Correct Answer is Right**
The correct answer, **D. Malaria**, is related to the role of PABA in inhibiting the growth of *Plasmodium* species, which are the parasites responsible for malaria. PABA competes with *p-aminobenzoic acid*, a substrate required by the parasite for folic acid synthesis, thereby acting as a prophylactic agent against malaria. This mechanism underlies its protective effect when present in breast milk.
## **Why Each Wrong Option is Incorrect**
- **Option A:** This option is incorrect because PABA does not have a well-documented role in preventing tuberculosis through breast milk.
- **Option B:** This option is incorrect as there is no established link between PABA in breast milk and the prevention of pneumonia.
- **Option C:** This option is incorrect because PABA's mechanism does not primarily involve preventing gastroenteritis.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that breastfed infants of mothers living in malaria-endemic areas receive protection against malaria through various factors in the breast milk, including potentially PABA. This highlights the importance of breastfeeding in areas with high malaria transmission.
## **Correct Answer:** D. Malaria
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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