Panda sign in gallium scan seen in –
**Core Concept**
The Panda sign in gallium scan refers to a characteristic pattern of increased uptake in the gallium scan, resembling the eyes of a panda. This pattern is typically seen in sarcoidosis, a systemic granulomatous disease that can affect various organs, including the lungs, lymph nodes, and skin.
**Why the Correct Answer is Right**
In sarcoidosis, the immune system forms non-caseating granulomas, which are collections of immune cells that attempt to wall off foreign substances. Gallium-67 citrate is a radioactive tracer that accumulates in areas of inflammation, including granulomas. The Panda sign is a result of gallium uptake in the lacrimal glands and the parotid glands, which are located near the eyes and mouth, respectively. This uptake creates a distinctive pattern that resembles the eyes of a panda.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because the Panda sign is not typically associated with lymphoma, which is a type of cancer that affects the immune system.
* **Option B:** This option is incorrect because the Panda sign is not a characteristic finding in tuberculosis, which is a bacterial infection that can cause granulomas.
* **Option C:** This option is incorrect because the Panda sign is not a feature of Crohn's disease, which is a type of inflammatory bowel disease.
**Clinical Pearl / High-Yield Fact**
The Panda sign is a classic radiographic finding in sarcoidosis, but it can also be seen in other conditions that cause granulomatous inflammation. It is essential to consider the clinical context and other imaging findings when interpreting gallium scans.
**Correct Answer:** B.