Paial thromboplastin time correlates with
Correct Answer: Function of platelets
Description: ref Robbins 8/e p120,666 ,;7/e p 69;9/e p80 Shoened APTT demonstrates hypercoagulation and high MOPEG levels indicate increased catecholamine metabolism. A direct correlation between APTT and MOPEG was found herein, demonstrating a link between catecholamines and the process of coagulation. Catecholamines may interact with the a2-adrenergic receptors located on platelets and conve factor XII to XIIa or through the kallikrein-kinin system, they may activate factor XII. The activation of factor XII initiates the intrinsic coagulation pathway, which is monitored by APTT. It is suggested to control patients with a shoened APTT and increased sympathetic activity with the aim of preventing secondary coagulation and cardiovascular accidents by administering anti-thrombotic and anti-adrenergic agents It correlates with clotting factor 12 and function of platelet
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