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7500 Pathology

A 3 year old boy is brought to the emergency depament after the acute onset of headache, vomiting, nuchal rigidity, and impaired mental status. MRI reveals a posterior fossa tumor that fills the 4th ventricle. Surgery is immediately staed, and intraoperative consultation leads to a “frozen section” diagnosis of medulloblastoma. Which of the following pathologic mechanisms most likely accounts for this child’s clinical presentation?

AAcute hemorrhage into the 4th ventricle
BAlteration of medullary function
CIncreased intracranial pressure
DInfiltration of the cerebellar vermis by the neoplasm
Pathology
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