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66602 Pathology

40-year-old woman dies after a long history of an illness characterized by dyspnea, ohopnea, hepatomegaly, distended neck veins, and peripheral edema. The cut surface of the liver as it appears at autopsy is shown in the first panel. The second panel shows the microscopic appearance of the liver. Which of the following disorders is the most likely cause of these findings?

AChronic alcoholism
BDiabetes mellitus
CNiemann-Pick disease
DRight-sided hea failure
Pathology
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66607 Medicine

A 42-year-old man with known valvular heart disease develops a fever for 1 week. He appears unwell; findings include a pansystolic murmur at the apex that radiates to the axilla and a soft S1 sound. He has petechiae on his conjunctival sac, linear hemorrhages under a few fingernails, and painful, tender, and erythematous nodules on some of the distal fingertips. Which of the following is the most responsible mechanism for these physical findings?

Adirect bacterial invasion
Bimmune response
Cvascular phenomena
Dvalvular damage
Medicine
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