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6526 Pathology

17-year-old boy presented with complain of petechiae. O/E ,sternal tenderness is present. BM biopsy show hypercellularity and more than 20% Lymphoblast. Peripheral smear show ||| TLC and presence of lymphoblast . On X ray. retrosternal mass is seen. All are true about condition patient is suffering except?

AIt has good prognosis
BNotch gene mutation present
CAn immature T-cell phenotype (Tdt/CD34/CD7 positive)
DThymic involvement is seen
Pathology
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6528 Pediatrics

A 6-year-old boy had been in his normal state of good health until a few hours prior to presentation to the emergency department. His mother reports that he began to have difficulty walking, and she noticed that he was falling and unable to maintain his balance. Which of the following is the most likely to allow diagnosis of his condition?

AObtain urine drug screen.
BMRI to evaluate his corpus callosum.
CClose scrutiny of his skin for telangiectasia.
DPerform a muscle biopsy of the gastrocnemius muscle.
Pediatrics
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