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65192 Surgery

A 55-year old male presents for evaluation of a lesion on his lower lip for the past year. He is employed as a landscaper and repos infrequent use of sun protection. He denies any peinent medical history. Physical examination reveals a 5 mm erythematous, ulcerative nodule located within the vermilion of the right lateral aspect of the lower lip. Biopsy confirms the presence of invasive squamous cell carcinoma and the patient is referred for Mohs micrographic surgical excision. Which of the following lymph nodes would be most critical to evaluate for metastasis?

ASubmental lymph nodes
BSubmandibular lymph nodes
CPosterior cervical chain
DJugulodigastric lymph node
Surgery
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65195 Biochemistry

A 28-year-old man presents to the emergency room (ER) with a large amount of blood and protein in his urine. He has had a sensorineural hearing loss since his teen years and has misshaped lenses (anterior lenticonus). The physician is suspicious of a genetic disorder that may lead to eventual kidney failure. If this is the case, the patient most likely has a mutation in which one of the following proteins?

ASpectrin
Ba1-Antitrypsin
CCollagen
DFibrillin
Biochemistry
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