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62130 Medicine

A man presents with bullous lesions on his face, armpit, and chest. He initially had them only in his mouth. They appear round and oval with serous fluid and some are “flabby.” When pressure is applied to the lesion, the fluid spreads laterally. A clinical diagnosis of pemphigus vulgaris (PV) is made. (See Figure below) Which of the following is the usual age of onset for this condition?

Aunder 10 years of age
B10-20 years of age
C20-40 years of age
D40-60 years of age
Medicine
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62136 Pathology

A 30-year-old man undergoes a lung biopsy, which shows multiple nodular lesions consisting of large epithelioid cells surrounded by lymphocytes and fibroblasts. There is an area of necrosis in the center of some nodules. Numerous acid-fast bacilli are demonstrated by Ziehl-Neelsen staining within the cytoplasm of epithelioid cells. Silver stains for fungi are negative. Which of the following is the MOST likely condition that predisposed the patient to this pulmonary disease?

AAcquired immunodeficiency syndrome (AIDS)
BCommon variable immunodeficiency
CCystic fibrosis
DDepressed level of consciousness
Pathology
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